Synscale Tech Inc.

Preclinical Research

Preclinical Evaluation Coordination Services

As the foundation of translational medicine, preclinical research connects fundamental scientific discoveries to real-world clinical applications. By systematically evaluating ADME/DMPK properties, pharmacodynamics (PD), and safety profiles, this process enhances the translational potential of drug candidates, increasing their likelihood of progressing into effective therapies.

At Synscale Tech Inc, we provide integrated coordination services for ADME/DMPK, pharmacodynamics (PD), and safety assessment of drug candidates through our network of trusted and certified partners. Our focus is to ensure a smooth transition from early research to clinical trials by connecting you with international industry-leading laboratories and CROs (Contract Research Organizations) for high-quality, regulatory-compliant data, and cost-effective studies.

Our Service Scope Includes:

  • In Vitro Biological Activity Assays
    Screening and quantification of pharmacological effects using validated cellular and biochemical models.
  • In Vivo Pharmacology & Toxicology
    Animal efficacy studies, acute/chronic toxicity tests, ADME profiling, and safety pharmacology conducted under GLP conditions through licensed partners.
  • Preclinical Study Coordination
    Protocol planning, partner selection, timeline management, data collection, and quality control for a wide range of preclinical studies.

Why Choose Synscale Tech:

  • Established Network: Partnerships with certified facilities across the U.S., China, and the EU.
  • Regulatory Compliance: All studies coordinated under GLP/GCP guidelines where applicable.
  • Quality Oversight: Continuous monitoring and data verification to ensure reproducibility and integrity.
  • Custom Solutions: Tailored workflows to match the unique needs of small molecule, biotech, or specialty pharma pipelines.

We act as your strategic partner, reducing administrative burden and accelerating time to clinical decision-making.

Disclaimer: Synscale Tech Inc. does not directly perform preclinical experiments. All experimental work is outsourced to certified third-party institutions in full compliance with local regulations.

Service Items：

In Vitro Testing

  1. Target Binding Assays
  2. Enzyme Activity Assays
  3. Cell Viability/Cytotoxicity Assays
  4. Receptor Binding/Activation Assays
  5. Permeability Assays (e.g., Caco-2, PAMPA)
  6. Metabolic Stability Assays (Microsomes/Hepatocytes)
  7. Drug-Drug Interaction (CYP Inhibition/Induction)
  8. Plasma Protein Binding Assays
  9. Hemolysis Assays

In Vivo Testing

  1. Pharmacokinetics (PK) Studies (ADME: Absorption, Distribution, Metabolism, Excretion)
  2. Pharmacodynamics (PD) Studies
  3. Toxicology Studies (Acute, Subacute, Chronic Toxicity)
  4. Genotoxicity Studies (Ames Test, Micronucleus Test)
  5. Carcinogenicity Studies
  6. Safety Pharmacology (Cardiovascular, CNS, Respiratory)
  7. Immunogenicity Studies
  8. Efficacy Studies (Disease Models)

Specialized Testing

  1. Bioanalytical Assays (LC-MS/MS, ELISA)
  2. Biomarker Analysis
  3. Toxicokinetics (TK) Studies